Carcinoma in situ of rectum (controls excluding all cancers)

CD2_INSITU_RECTUM_EXALLC

Endpoint definition

Endpoint definition steps

FinnGen

Phenotype data

1. Apply sex-specific rule

None

-

2. Check conditions

  • not C3_RECTUM
-

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 D01.2&
  • Hospital discharge: ICD-9 2304
  • Cause of death: ICD-10 D01.2&
  • Cause of death: ICD-9 2304
  • Cancer registry: Topography ICD-O-3 C20
  • Cancer registry: Morphology ICD-O-3 ANY
  • Cancer registry: Behaviour codes 2

3 out of 7 registries used, show all original rules.

-

4. Check minimum number of events

None

-

5. Include endpoints

None

-

6. Filter based on genotype QC (FinnGen only)

None

-

Control definitions (FinnGen only)

Control exclude C3_CANCER, C3_CANCER_WIDE

Extra metadata

Level in the ICD hierarchy 3
First used in FinnGen datafreeze DF9
Parent code in ICD-10 D01
Name in latin Carcinoma in situ hepatis

Case counts by codes

FinnGen case counts by registry codes:

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Summary Statistics

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 174 86 84
Only index persons 103 52 51
Unadjusted period prevalence (%)
Whole population 0.00 0.00 0.00
Only index persons 0.00 0.00 0.00
Median age at first event (years)
Whole population 71.50 70.93 71.69
Only index persons 70.19 69.41 70.98

-FinnGen-

Key figures

All Female Male
Number of individuals 83 38 45
Unadjusted period prevalence (%) 0.02 0.02 0.02
Median age at first event (years) 70.15 70.45 69.89

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

Mortality – FinRegistry

Relationships between endpoints

Index endpoint: CD2_INSITU_RECTUM_EXALLC – Carcinoma in situ of rectum (controls excluding all cancers)

GWS hits: -

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