Carcinoma in situ of cervix uteri (controls excluding all cancers)

CD2_INSITU_CERVIX_UTERI_EXALLC

Endpoint definition

Endpoint definition steps

FinnGen

Phenotype data

1. Apply sex-specific rule

only females

-

2. Check conditions

  • not C3_CERVIX_UTERI
-

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 D06
  • Cause of death: ICD-10 D06
  • Cancer registry: Topography ICD-O-3 C53
  • Cancer registry: Morphology ICD-O-3 ANY
  • Cancer registry: Behaviour codes 2

3 out of 7 registries used, show all original rules.

-

4. Check minimum number of events

None

-

5. Include endpoints

-

6. Filter based on genotype QC (FinnGen only)

None

-

Control definitions (FinnGen only)

Control exclude C3_CANCER, C3_CANCER_WIDE

Extra metadata

Level in the ICD hierarchy 2
First used in FinnGen datafreeze DF9
Parent code in ICD-10 D00-D09
Name in latin Carcinoma in situ vaginae

Case counts by codes

FinnGen case counts by registry codes:

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Summary Statistics

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 5402 5402 -
Only index persons 5151 5151 -
Unadjusted period prevalence (%)
Whole population 0.15 0.15 -
Only index persons 0.19 0.19 -
Median age at first event (years)
Whole population - 36.09 -
Only index persons - 35.80 -

-FinnGen-

Key figures

All Female Male
Number of individuals 2458 2458 -
Unadjusted period prevalence (%) 1.07 1.07 -
Median age at first event (years) 35.41 35.41 -

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

Mortality – FinRegistry

Relationships between endpoints

Index endpoint: CD2_INSITU_CERVIX_UTERI_EXALLC – Carcinoma in situ of cervix uteri (controls excluding all cancers)

GWS hits: 1

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