Leiomyoma of uterus

CD2_BENIGN_LEIOMYOMA_UTERI

uterine fibroid: A benign smooth muscle neoplasm arising from the body of the uterus. It is characterized by the presence of spindle cells with cigar-shaped nuclei, interlacing fascicles, and a whorled pattern.

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Endpoint definition

Endpoint definition steps

FinnGen

Phenotype data

429209

1. Apply sex-specific rule

only females

239906

2. Check conditions

None

239906

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 D25
  • Hospital discharge: ICD-9 218
  • Hospital discharge: ICD-8 21899
  • Cause of death: ICD-10 D25
  • Cause of death: ICD-9 218
  • Cause of death: ICD-8 21899

2 out of 7 registries used, show all original rules.

35628

4. Check minimum number of events

None

35628

5. Include endpoints

None

35628

6. Filter based on genotype QC (FinnGen only)

34421

Control definitions (FinnGen only)

Controls for this endpoint are individuals that are not cases.

Extra metadata

Level in the ICD hierarchy 2
First used in FinnGen datafreeze DF2
Parent code in ICD-10 D10-D36
Name in latin Leiomyoma uteri

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

This endpoint is excluded from FinRegistry analyses (omitted endpoint).

-FinnGen-

Key figures

All Female Male
Number of individuals 34421 34421 -
Unadjusted period prevalence (%) 14.95 14.95 -
Median age at first event (years) 46.65 46.65 -

-FinnGen-

Age distribution of first events

-FinnGen-

Year distribution of first events

-FinnGen-

Cumulative Incidence Function

Mortality – FinRegistry

This endpoint is excluded from FinRegistry analyses (omitted endpoint).

Relationships between endpoints

Index endpoint: CD2_BENIGN_LEIOMYOMA_UTERI – Leiomyoma of uterus

GWS hits: 105

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