Papillary adenocarcinoma of thyroid gland (controls excluding all cancers)

C3_THYROID_PAPILLARY_ADENO_EXALLC

Endpoint definition

Endpoint definition steps

FinnGen

Phenotype data

1. Apply sex-specific rule

None

-

2. Check conditions

None

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Cause of death: ICD-10 C73.91&
  • Cause of death: ICD-9 193A
  • Cancer registry: Topography ICD-O-3 C73
  • Cancer registry: Morphology ICD-O-3 8260
  • Cancer registry: Behaviour codes 3

2 out of 7 registries used, show all original rules.

-

4. Check minimum number of events

None

-

5. Include endpoints

None

-

6. Filter based on genotype QC (FinnGen only)

None

-

Control definitions (FinnGen only)

Control exclude C3_CANCER, C3_CANCER_WIDE

Extra metadata

First used in FinnGen datafreeze DF8

Similar endpoints

Case counts by codes

FinnGen case counts by registry codes:

No upset plot: script not run.

No upset table: script not run.

Summary Statistics

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 10847 8351 2412
Only index persons 9523 7488 2035
Unadjusted period prevalence (%)
Whole population 0.20 0.24 0.07
Only index persons 0.23 0.28 0.08
Median age at first event (years)
Whole population 49.55 48.74 52.35
Only index persons 48.19 47.48 50.81

-FinnGen-

Key figures

All Female Male
Number of individuals 1471 1120 351
Unadjusted period prevalence (%) 0.42 0.49 0.19
Median age at first event (years) 49.31 47.14 56.20

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

Mortality – FinRegistry

Relationships between endpoints

Index endpoint: C3_THYROID_PAPILLARY_ADENO_EXALLC – Papillary adenocarcinoma of thyroid gland (controls excluding all cancers)

GWS hits: 8

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