Adenocarcinoma, papilloma adenocarcinoma and mucinous carcinomas of rectum (controls excluding all cancers)

C3_RECTUM_ADENO_MUCINO_EXALLC

Endpoint definition

Endpoint definition steps

FinnGen

Phenotype data

1. Apply sex-specific rule

None

-

2. Check conditions

None

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Cause of death: ICD-10 C20.92&
  • Cancer registry: Topography ICD-O-3 C19|C20
  • Cancer registry: Morphology ICD-O-3 8140|8480
  • Cancer registry: Behaviour codes 3

2 out of 7 registries used, show all original rules.

-

4. Check minimum number of events

None

-

5. Include endpoints

None

-

6. Filter based on genotype QC (FinnGen only)

None

-

Control definitions (FinnGen only)

Control exclude C3_CANCER, C3_CANCER_WIDE

Extra metadata

First used in FinnGen datafreeze DF9
Name in latin Carcinoma in situ cavitatis oris, oesophagi sive ventriculi

Similar endpoints

List of similar endpoints to Adenocarcinoma, papilloma adenocarcinoma and mucinous carcinomas of rectum (controls excluding all cancers) based on the number of shared cases.

Venn diagram with an highlighted set fully inside another set Broader endpoints:

Venn diagram with a set fully inside an highlighted set Narrower endpoints:

Case counts by codes

FinnGen case counts by registry codes:

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Summary Statistics

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 29932 12369 16907
Only index persons 18465 7909 10556
Unadjusted period prevalence (%)
Whole population 0.43 0.35 0.47
Only index persons 0.35 0.29 0.40
Median age at first event (years)
Whole population 68.81 69.29 68.51
Only index persons 68.75 68.95 68.59

-FinnGen-

Key figures

All Female Male
Number of individuals 2545 909 1636
Unadjusted period prevalence (%) 0.72 0.39 0.90
Median age at first event (years) 67.61 66.18 68.41

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

Mortality – FinRegistry

Relationships between endpoints

Index endpoint: C3_RECTUM_ADENO_MUCINO_EXALLC – Adenocarcinoma, papilloma adenocarcinoma and mucinous carcinomas of rectum (controls excluding all cancers)

GWS hits: 8

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