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Malignant neoplasm of peripheral nerves and autonomic nervous system

DOID Endpoint Browser

C3_PERIPHERAL_NERVES_AUTONOMIC3_NERVESYSTEM

tumour of cranial and spinal nerves: ['A benign or malignant neoplasm arising from a peripheral nerve or the perineural sheaths.', 'Neoplasms which arise from peripheral nerve tissue. This includes NEUROFIBROMAS; SCHWANNOMAS; GRANULAR CELL TUMORS; and malignant peripheral NERVE SHEATH NEOPLASMS. (From DeVita Jr et al., Cancer: Principles and Practice of Oncology, 5th ed, pp1750-1)']

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Endpoint definition

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Endpoint definition steps

FinnGen

Phenotype data

429209

1. Apply sex-specific rule

None

429209

2. Check conditions

None

429209

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Cause of death: ICD-10 — C47
  • Cause of death: ICD-9 — 1928
  • Cause of death: ICD-8 — 192[4-5]
  • Cancer registry: Topography ICD-O-3 — C47
  • Cancer registry: Morphology ICD-O-3 — ANY
  • Cancer registry: Behaviour codes — 3

2 out of 7 registries used, show all original rules.

32

4. Check minimum number of events

None

32

5. Include endpoints

None

32

6. Filter based on genotype QC (FinnGen only)

32

Control definitions (FinnGen only)

Controls for this endpoint are individuals that are not cases.

Extra metadata

Level in the ICD hierarchy 3
First used in FinnGen datafreeze DF9

Similar endpoints

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List of similar endpoints to Malignant neoplasm of peripheral nerves and autonomic nervous system based on the number of shared cases.

Venn diagram with an highlighted set fully inside another set Broader endpoints:

Venn diagram with a set fully inside an highlighted set Narrower endpoints:

Case counts by codes

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FinnGen case counts by registry codes:

Not enough data for upset plot.

Not enough data for upset table.

Summary Statistics

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-FinRegistry-

This endpoint is excluded from FinRegistry analyses (omitted endpoint).

-FinnGen-

Key figures

All Female Male
Number of individuals 32 15 17
Unadjusted period prevalence (%) 0.01 0.01 0.01
Median age at first event (years) 23.70 24.61 22.89

-FinnGen-

Age distribution of first events

-FinnGen-

Year distribution of first events

-FinnGen-

Cumulative Incidence Function

Not a core endpoint, no data to show.

Mortality – FinRegistry

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This endpoint is excluded from FinRegistry analyses (omitted endpoint).

Relationships between endpoints

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Index endpoint: C3_PERIPHERAL_NERVES_AUTONOMIC3_NERVESYSTEM – Malignant neoplasm of peripheral nerves and autonomic nervous system

GWS hits: -

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