Myelodysplastic syndrome (controls excluding all cancers)

C3_MYELODYSP_SYNDR_EXALLC

Endpoint definition

Endpoint definition steps

FinnGen

Phenotype data

1. Apply sex-specific rule

None

-

2. Check conditions

None

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Cause of death: ICD-10 D46
  • Cancer registry: Topography ICD-O-3 ANY
  • Cancer registry: Morphology ICD-O-3 9980|998[2-5]|9989
  • Cancer registry: Behaviour codes 3

2 out of 7 registries used, show all original rules.

-

4. Check minimum number of events

None

-

5. Include endpoints

None

-

6. Filter based on genotype QC (FinnGen only)

None

-

Control definitions (FinnGen only)

Control exclude C3_CANCER, C3_CANCER_WIDE

Extra metadata

Level in the ICD hierarchy C
First used in FinnGen datafreeze DF8

Case counts by codes

FinnGen case counts by registry codes:

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Summary Statistics

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 3250 1504 1679
Only index persons 1987 930 1057
Unadjusted period prevalence (%)
Whole population 0.05 0.04 0.05
Only index persons 0.04 0.03 0.04
Median age at first event (years)
Whole population 79.47 81.26 77.93
Only index persons 79.50 81.45 77.78

-FinnGen-

Key figures

All Female Male
Number of individuals 206 61 145
Unadjusted period prevalence (%) 0.06 0.03 0.08
Median age at first event (years) 77.56 79.52 76.73

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

Mortality – FinRegistry

Relationships between endpoints

Index endpoint: C3_MYELODYSP_SYNDR_EXALLC – Myelodysplastic syndrome (controls excluding all cancers)

GWS hits: -

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