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Multiple myeloma (controls excluding all cancers)

Endpoint Browser PheWeb

C3_MULT_MYELOMA_EXALLC

Endpoint definition

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Endpoint definition steps

FinnGen

Phenotype data

1. Apply sex-specific rule

None

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2. Check conditions

None

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Cause of death: ICD-10 — C90.0
  • Cause of death: ICD-9 — 2030A
  • Cancer registry: Topography ICD-O-3 — ANY
  • Cancer registry: Morphology ICD-O-3 — 9732
  • Cancer registry: Behaviour codes — 3

2 out of 7 registries used, show all original rules.

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4. Check minimum number of events

None

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5. Include endpoints

None

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6. Filter based on genotype QC (FinnGen only)

None

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Control definitions (FinnGen only)

Control exclude C3_CANCER, C3_CANCER_WIDE

Extra metadata

First used in FinnGen datafreeze DF8

Case counts by codes

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FinnGen case counts by registry codes:

No upset plot: script not run.

No upset table: script not run.

Summary Statistics

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-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 11460 5512 5712
Only index persons 5568 2719 2849
Unadjusted period prevalence (%)
Whole population 0.16 0.16 0.16
Only index persons 0.10 0.10 0.11
Median age at first event (years)
Whole population 70.36 71.38 69.46
Only index persons 71.38 72.60 70.21

-FinnGen-

Key figures

All Female Male
Number of individuals 623 262 361
Unadjusted period prevalence (%) 0.16 0.11 0.20
Median age at first event (years) 69.55 68.88 70.04

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

Mortality – FinRegistry

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Relationships between endpoints

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Index endpoint: C3_MULT_MYELOMA_EXALLC – Multiple myeloma (controls excluding all cancers)

GWS hits: 1

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