Brain meningioma (controls excluding all cancers)

C3_MENINGIOMA_EXALLC

Endpoint definition

Endpoint definition steps

FinnGen

Phenotype data

1. Apply sex-specific rule

None

-

2. Check conditions

None

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Cause of death: ICD-10 C70
  • Cause of death: ICD-9 1921|1923
  • Cause of death: ICD-8 192[1-2]
  • Cancer registry: Topography ICD-O-3 C70
  • Cancer registry: Morphology ICD-O-3 953[0-4]|953[7-9]
  • Cancer registry: Behaviour codes ANY

2 out of 7 registries used, show all original rules.

-

4. Check minimum number of events

None

-

5. Include endpoints

None

-

6. Filter based on genotype QC (FinnGen only)

None

-

Control definitions (FinnGen only)

Control exclude C3_CANCER, C3_CANCER_WIDE

Extra metadata

Level in the ICD hierarchy C
First used in FinnGen datafreeze DF8

Case counts by codes

FinnGen case counts by registry codes:

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Summary Statistics

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 12584 9165 3290
Only index persons 9814 7446 2368
Unadjusted period prevalence (%)
Whole population 0.22 0.26 0.09
Only index persons 0.23 0.27 0.09
Median age at first event (years)
Whole population 59.77 59.48 60.56
Only index persons 58.74 58.41 59.76

-FinnGen-

Key figures

All Female Male
Number of individuals 1316 979 337
Unadjusted period prevalence (%) 0.36 0.43 0.19
Median age at first event (years) 58.22 57.07 61.56

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

Mortality – FinRegistry

Relationships between endpoints

Index endpoint: C3_MENINGIOMA_EXALLC – Brain meningioma (controls excluding all cancers)

GWS hits: 3

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