Malignant neoplasm of anus and anal canal (controls excluding all cancers)

C3_ANUS_ANALCANAL_EXALLC

Endpoint definition

Endpoint definition steps

FinnGen

Phenotype data

1. Apply sex-specific rule

None

-

2. Check conditions

None

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Cause of death: ICD-10 C21
  • Cause of death: ICD-9 154[2-3]
  • Cause of death: ICD-8 1542
  • Cancer registry: Topography ICD-O-3 C21
  • Cancer registry: Morphology ICD-O-3 ANY
  • Cancer registry: Behaviour codes 3

2 out of 7 registries used, show all original rules.

-

4. Check minimum number of events

None

-

5. Include endpoints

None

-

6. Filter based on genotype QC (FinnGen only)

None

-

Control definitions (FinnGen only)

Control exclude C3_CANCER, C3_CANCER_WIDE

Extra metadata

Level in the ICD hierarchy 3
First used in FinnGen datafreeze DF9

Case counts by codes

FinnGen case counts by registry codes:

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Summary Statistics

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 1355 788 545
Only index persons 906 556 350
Unadjusted period prevalence (%)
Whole population 0.02 0.02 0.02
Only index persons 0.02 0.02 0.01
Median age at first event (years)
Whole population 66.79 66.61 67.23
Only index persons 65.20 64.72 65.96

-FinnGen-

Key figures

All Female Male
Number of individuals 98 59 39
Unadjusted period prevalence (%) 0.02 0.03 0.02
Median age at first event (years) 63.98 62.08 66.85

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

Mortality – FinRegistry

Relationships between endpoints

Index endpoint: C3_ANUS_ANALCANAL_EXALLC – Malignant neoplasm of anus and anal canal (controls excluding all cancers)

GWS hits: -

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