Use of disulfiram, acamprosate or naltrexone

ALCO_PRESCRIPTION

Endpoint definition

Endpoint definition steps

FinnGen

Phenotype data

429209

1. Apply sex-specific rule

None

429209

2. Check conditions

None

429209

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Medicine purchases: ATC N07BB01|N07BB03|N07BB04

1 out of 7 registries used, show all original rules.

3070

4. Check minimum number of events

Min. number of events 3
3070

5. Include endpoints

None

3070

6. Filter based on genotype QC (FinnGen only)

2999

Control definitions (FinnGen only)

Controls for this endpoint are individuals that are not cases.

Extra metadata

Level in the ICD hierarchy 2
First used in FinnGen datafreeze DF2

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 26141 6777 19291
Only index persons 24858 6542 18316
Unadjusted period prevalence (%)
Whole population 0.45 0.19 0.54
Only index persons 0.58 0.24 0.70
Median age at first event (years)
Whole population 42.28 42.46 42.23
Only index persons 42.16 42.34 42.09

-FinnGen-

Key figures

All Female Male
Number of individuals 2999 967 2032
Unadjusted period prevalence (%) 0.89 0.42 1.12
Median age at first event (years) 42.79 41.16 43.57

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

Mortality – FinRegistry

Relationships between endpoints

Index endpoint: ALCO_PRESCRIPTION – Use of disulfiram, acamprosate or naltrexone

GWS hits: 1

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