Alcohol-induced acute pancreatitis

ALCOPANCACU

alcoholic pancreatitis: Acute or chronic inflammation of the pancreas due to excessive alcohol drinking. Alcoholic pancreatitis usually presents as an acute episode but it is a chronic progressive disease in alcoholics.

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Endpoint definition

Endpoint definition steps

FinnGen

Phenotype data

429209

1. Apply sex-specific rule

None

429209

2. Check conditions

None

429209

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 K85.2
  • Hospital discharge: ICD-9 5770D|5770E
  • Cause of death: ICD-10 K85.2
  • Cause of death: ICD-9 5770D|5770E

2 out of 7 registries used, show all original rules.

1041

4. Check minimum number of events

None

1041

5. Include endpoints

None

1041

6. Filter based on genotype QC (FinnGen only)

1021

Control definitions (FinnGen only)

Controls for this endpoint are individuals that are not cases.

Extra metadata

Level in the ICD hierarchy 2
First used in FinnGen datafreeze DF2
Parent code in ICD-10 K85

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 13938 2274 11487
Only index persons 9836 1787 8049
Unadjusted period prevalence (%)
Whole population 0.28 0.07 0.32
Only index persons 0.26 0.07 0.31
Median age at first event (years)
Whole population 45.74 48.04 45.21
Only index persons 46.50 48.71 46.01

-FinnGen-

Key figures

All Female Male
Number of individuals 1021 185 836
Unadjusted period prevalence (%) 0.39 0.08 0.46
Median age at first event (years) 48.46 48.12 48.53

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

Mortality – FinRegistry

Relationships between endpoints

Index endpoint: ALCOPANCACU – Alcohol-induced acute pancreatitis

GWS hits: 3

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