Certain zoonotic bacterial diseases

AB1_ZOONOTIC_BACTERIAL

Yersinia pestis infectious disease: Plague is a severe bacterial infection caused by the gram-negative bacterium Yersinia pestis.

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Endpoint definition

Endpoint definition steps

FinnGen

Phenotype data

429209

1. Apply sex-specific rule

None

429209

2. Check conditions

None

429209

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 A20-A28
  • Hospital discharge: ICD-9 02[0-7]|B783A
  • Hospital discharge: ICD-8 02[0-7]
  • Cause of death: ICD-10 A20-A28
  • Cause of death: ICD-9 02[0-7]|B783A
  • Cause of death: ICD-8 02[0-7]

2 out of 7 registries used, show all original rules.

516

4. Check minimum number of events

None

516

5. Include endpoints

516

6. Filter based on genotype QC (FinnGen only)

500

Control definitions (FinnGen only)

Controls for this endpoint are individuals that are not cases.

Extra metadata

Level in the ICD hierarchy 2
First used in FinnGen datafreeze DF2

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 6494 3019 3435
Only index persons 5630 2662 2968
Unadjusted period prevalence (%)
Whole population 0.09 0.09 0.10
Only index persons 0.11 0.10 0.11
Median age at first event (years)
Whole population 47.98 48.65 47.21
Only index persons 45.99 46.97 45.11

-FinnGen-

Key figures

All Female Male
Number of individuals 500 246 254
Unadjusted period prevalence (%) 0.12 0.11 0.14
Median age at first event (years) 50.64 47.92 53.27

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

Mortality – FinRegistry

Relationships between endpoints

Index endpoint: AB1_ZOONOTIC_BACTERIAL – Certain zoonotic bacterial diseases

GWS hits: -

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