Streptococcal septicaemia

AB1_STREPTO_SEPSIS

Endpoint definition

Endpoint definition steps

FinnGen

Phenotype data

429209

1. Apply sex-specific rule

None

429209

2. Check conditions

None

429209

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 A40
  • Hospital discharge: ICD-9 038[0]
  • Hospital discharge: ICD-8 038[0]
  • Cause of death: ICD-10 A40
  • Cause of death: ICD-9 038[0]
  • Cause of death: ICD-8 038[0]

2 out of 7 registries used, show all original rules.

2654

4. Check minimum number of events

None

2654

5. Include endpoints

None

2654

6. Filter based on genotype QC (FinnGen only)

2543

Control definitions (FinnGen only)

Control exclude AB1_OTHER_BACTERIAL

Extra metadata

Level in the ICD hierarchy 4
First used in FinnGen datafreeze DF5

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 30449 13253 16974
Only index persons 24844 10973 13871
Unadjusted period prevalence (%)
Whole population 0.43 0.38 0.47
Only index persons 0.47 0.40 0.53
Median age at first event (years)
Whole population 60.80 62.34 59.49
Only index persons 60.39 61.75 59.32

-FinnGen-

Key figures

All Female Male
Number of individuals 2543 1012 1531
Unadjusted period prevalence (%) 0.68 0.44 0.84
Median age at first event (years) 64.17 59.87 67.01

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

Mortality – FinRegistry

Relationships between endpoints

Index endpoint: AB1_STREPTO_SEPSIS – Streptococcal septicaemia

GWS hits: 1

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