Protozoal diseases

AB1_PROTOZOAL

toxoplasmosis: A parasitic disease contracted by the ingestion or fetal transmission of toxoplasma gondii.

Endpoint definition

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Endpoint definition steps	FinnGen
Phenotype data	429209
1. Apply sex-specific rule None	429209
2. Check conditions None	429209
3. Check pre-conditions, main-only, mode, registry filters Registry filters: Hospital discharge: ICD-10 — B50-B64 Hospital discharge: ICD-9 — 08[4-6]\|130\|136[3-4]\|0889 Hospital discharge: ICD-8 — 08[6-7]\|130\|084\|13601 Cause of death: ICD-10 — B50-B64 Cause of death: ICD-9 — 08[4-6]\|130\|136[3-4]\|0889 Cause of death: ICD-8 — 08[6-7]\|130\|084\|13601 2 out of 7 registries used, show all original rules.	-
4. Check minimum number of events None	-
5. Include endpoints AB1_MALARIA AB1_LEISHMANIASIS AB1_AFRICAN_TRYPANOSOMIASIS AB1_CHAGA AB1_TOXOPLASMOSIS AB1_PNEUMOCYSTOSIS AB1_PROTOZOAL_NOS	740
6. Filter based on genotype QC (FinnGen only)	705

Control definitions (FinnGen only)

Controls for this endpoint are individuals that are not cases.

Extra metadata

Level in the ICD hierarchy 2

First used in FinnGen datafreeze DF2

NAME	AB1_PROTOZOAL
CONTROL_EXCLUDE
CONTROL_PRECONDITIONS
CONTROL_CONDITIONS
SEX
INCLUDE	AB1_MALARIA\|AB1_LEISHMANIASIS\|AB1_AFRICAN_TRYPANOSOMIASIS\|AB1_CHAGA\|AB1_TOXOPLASMOSIS\|AB1_PNEUMOCYSTOSIS\|AB1_PROTOZOAL_NOS
PRE_CONDITIONS
CONDITIONS
OUTPAT_ICD
OUTPAT_OPER
HD_MAINONLY
HD_ICD_10_ATC
HD_ICD_10	B5[0-9]\|B6[0-4]
HD_ICD_9	08[4-6]\|130\|136[3-4]\|0889
HD_ICD_8	08[6-7]\|130\|084\|13601
HD_ICD_10_EXCL
HD_ICD_9_EXCL
HD_ICD_8_EXCL
COD_MAINONLY
COD_ICD_10	B5[0-9]\|B6[0-4]
COD_ICD_9	08[4-6]\|130\|136[3-4]\|0889
COD_ICD_8	08[6-7]\|130\|084\|13601
COD_ICD_10_EXCL
COD_ICD_9_EXCL
COD_ICD_8_EXCL
OPER_NOM
OPER_HL
OPER_HP1
OPER_HP2
KELA_REIMB
KELA_REIMB_ICD
KELA_ATC_NEEDOTHER
KELA_ATC
KELA_VNRO_NEEDOTHER
KELA_VNRO
CANC_TOPO
CANC_TOPO_EXCL
CANC_MORPH
CANC_MORPH_EXCL
CANC_BEHAV

Similar endpoints

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List of similar endpoints to Protozoal diseases based on the number of shared cases.

Broader endpoints:

Narrower endpoints:

Case counts by codes

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FinnGen case counts by registry codes:

Upset plot

Full data table

Summary Statistics

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-FinRegistry-

Key figures

	All	Female	Male
Number of individuals
Whole population	6426	2933	3386
Only index persons	5431	2564	2867
Unadjusted period prevalence (%)
Whole population	0.09	0.08	0.09
Only index persons	0.10	0.09	0.11
Median age at first event (years)
Whole population	46.07	44.91	47.33
Only index persons	44.50	43.08	45.77

-FinnGen-

Key figures

	All	Female	Male
Number of individuals	705	363	342
Unadjusted period prevalence (%)	0.17	0.16	0.19
Median age at first event (years)	55.18	50.42	60.22

≡ Risteys

FR+FG R10

FinnGen Risteys R10

FinnGen Risteys R9

FinnGen Risteys R8

FinnGen Risteys R7

FinnGen Risteys R6

FinnGen Risteys R5

FinnGen Risteys R4

FinnGen Risteys R3

Protozoal diseases

Endpoint definition

Endpoint definition steps

FinnGen

Phenotype data

1. Apply sex-specific rule

2. Check conditions

3. Check pre-conditions, main-only, mode, registry filters

4. Check minimum number of events

5. Include endpoints

6. Filter based on genotype QC (FinnGen only)

All original rules

Similar endpoints

Case counts by codes

Upset plot

Case counts by code for Protozoal diseases (AB1_PROTOZOAL)

Summary Statistics

-FinRegistry-

Key figures

-FinnGen-

Key figures

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

Mortality – FinRegistry

Relationships between endpoints