Helminthiases

AB1_HELMINTIASES

Trematode Infections: Infections caused by infestation with worms of the class Trematoda.

Endpoint definition

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Endpoint definition steps	FinnGen
Phenotype data	429209
1. Apply sex-specific rule None	429209
2. Check conditions None	429209
3. Check pre-conditions, main-only, mode, registry filters Registry filters: Hospital discharge: ICD-10 — B65-B83 Hospital discharge: ICD-9 — 12[0-3] Hospital discharge: ICD-8 — 12[0-9]\|13602 Cause of death: ICD-10 — B65-B83 Cause of death: ICD-9 — 12[0-3] Cause of death: ICD-8 — 12[0-9]\|13602 2 out of 7 registries used, show all original rules.	518
4. Check minimum number of events None	518
5. Include endpoints AB1_SCHISTOSOMIASIS AB1_OTHER_FLUKE AB1_ECHINOCOCCOSIS AB1_TAENIASIS AB1_CYSTICERCOSIS AB1_DIPHYLO_AND_SPARGANOSIS AB1_OTHER_CESTODE AB1_DRACUNCULIASIS AB1_ONCHOCERCIASIS AB1_FILARIASIS AB1_TRICHINELLOSIS AB1_HOOKWORM AB1_ASCARIASIS AB1_STRONGYLOIDIASIS AB1_TRICHURIASIS AB1_ENTEROBIASIS AB1_INT_HELMINTIASES_NOS AB1_HELMINTHIASES_NOS	555
6. Filter based on genotype QC (FinnGen only)	523

Control definitions (FinnGen only)

Controls for this endpoint are individuals that are not cases.

Extra metadata

Level in the ICD hierarchy 2

First used in FinnGen datafreeze DF6V3

NAME	AB1_HELMINTIASES
CONTROL_EXCLUDE
CONTROL_PRECONDITIONS
CONTROL_CONDITIONS
SEX
INCLUDE	AB1_SCHISTOSOMIASIS\|AB1_OTHER_FLUKE\|AB1_ECHINOCOCCOSIS\|AB1_TAENIASIS\|AB1_CYSTICERCOSIS\|AB1_DIPHYLO_AND_SPARGANOSIS\|AB1_OTHER_CESTODE\|AB1_DRACUNCULIASIS\|AB1_ONCHOCERCIASIS\|AB1_FILARIASIS\|AB1_TRICHINELLOSIS\|AB1_HOOKWORM\|AB1_ASCARIASIS\|AB1_STRONGYLOIDIASIS\|AB1_TRICHURIASIS\|AB1_ENTEROBIASIS\|AB1_INT_HELMINTIASES_NOS\|AB1_HELMINTHIASES_NOS
PRE_CONDITIONS
CONDITIONS
OUTPAT_ICD
OUTPAT_OPER
HD_MAINONLY
HD_ICD_10_ATC
HD_ICD_10	B6[5-9]\|B7[0-9]\|B8[0-3]
HD_ICD_9	12[0-3]
HD_ICD_8	12[0-9]\|13602
HD_ICD_10_EXCL
HD_ICD_9_EXCL
HD_ICD_8_EXCL
COD_MAINONLY
COD_ICD_10	B6[5-9]\|B7[0-9]\|B8[0-3]
COD_ICD_9	12[0-3]
COD_ICD_8	12[0-9]\|13602
COD_ICD_10_EXCL
COD_ICD_9_EXCL
COD_ICD_8_EXCL
OPER_NOM
OPER_HL
OPER_HP1
OPER_HP2
KELA_REIMB
KELA_REIMB_ICD
KELA_ATC_NEEDOTHER
KELA_ATC
KELA_VNRO_NEEDOTHER
KELA_VNRO
CANC_TOPO
CANC_TOPO_EXCL
CANC_MORPH
CANC_MORPH_EXCL
CANC_BEHAV

Similar endpoints

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List of similar endpoints to Helminthiases based on the number of shared cases.

Broader endpoints:

Narrower endpoints:

Case counts by codes

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FinnGen case counts by registry codes:

Upset plot

Full data table

Summary Statistics

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-FinRegistry-

Key figures

	All	Female	Male
Number of individuals
Whole population	8913	4944	3842
Only index persons	5959	3558	2401
Unadjusted period prevalence (%)
Whole population	0.13	0.14	0.11
Only index persons	0.12	0.13	0.09
Median age at first event (years)
Whole population	33.97	31.17	37.09
Only index persons	29.01	28.92	29.15

-FinnGen-

Key figures

	All	Female	Male
Number of individuals	523	316	207
Unadjusted period prevalence (%)	0.13	0.14	0.11
Median age at first event (years)	36.59	33.58	41.19

≡ Risteys

FR+FG R10

FinnGen Risteys R10

FinnGen Risteys R9

FinnGen Risteys R8

FinnGen Risteys R7

FinnGen Risteys R6

FinnGen Risteys R5

FinnGen Risteys R4

FinnGen Risteys R3

Helminthiases

Endpoint definition

Endpoint definition steps

FinnGen

Phenotype data

1. Apply sex-specific rule

2. Check conditions

3. Check pre-conditions, main-only, mode, registry filters

4. Check minimum number of events

5. Include endpoints

6. Filter based on genotype QC (FinnGen only)

All original rules

Similar endpoints

Case counts by codes

Upset plot

Case counts by code for Helminthiases (AB1_HELMINTIASES)

Summary Statistics

-FinRegistry-

Key figures

-FinnGen-

Key figures

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

Mortality – FinRegistry

Relationships between endpoints